CALLOSAL LIPOMA - keywords
callosal lipoma
references to lipoma of the corpus callosum
r
e
f
e
r
e
n
c
e
s
n
a
v
i
g
a
t
o
r
<
Atallah A, Lacalm A, Massoud M, Massardier J, Gaucherand P, Guibaud L. Prenatal diagnosis of pericallosal curvilinear lipoma: specific imaging pattern and diagnostic pitfalls. Ultrasound Obstet Gynecol. 2018 Feb;51(2):269-273.
Baker LB, Conroy J, Donoghue V, Mullarkey M, Shah N, Murphy N, Murphy J, Ennis S, Lynch SA. Agenesis of the corpus callosum with midline lipoma associated with an Xp22.31-Xp22.12 deletion. Clin Dysmorphol. 2011 Jan;20(1):21-25.
Boechat MI, Kangarloo H, Diament MJ, Krauthamer R (1983) Lipoma of the corpus callosum: sonographic appearance. J Clin Ultrasound 11:447-8.
Castori M, Rinaldi R, Bianchi A, Caponetti A, Assumma M, Grammatico P. Pai syndrome: first patient with agenesis of the corpus callosum and literature review. Birth Defects Res A Clin Mol Teratol. 2007 Oct;79(10):673-9.
Fisher RM, Cremin BJ (1988) Lipoma of the corpus callosum: diagnosis by ultrasound and magnetic resonance. Pediatric Radiology 18:409–410.
Gradowska K, Czech-Kowalska J, Jurkiewicz E, Komornicka J, Dobrzańska A. Lipomas of the central nervous system in the newborns - a report of eight cases. Pol J Radiol. 2011 Oct;76(4):63-8.
Imaizumi SO, Pleasure JR, Zubrow AB. Lesion mistaken for hemorrhage in a premature infant: lipoma of corpus callosum. Pediatr Neurol. 1988 Sep-Oct;4(5):313-6.
Mehta NM, Hartnoll G (2001) Congenital CMV with callosal lipoma and agenesis. Pediatr Neurol 24:222-4.
Melin GI, Keller MS (1992) Pericallosal lipoma extending through the choroidal fissure: US/CT/MRI correlation. Neuroradiology 34:402-3.Olivero F, Foiadelli T, Luzzi S, Marseglia GL, Savasta S. Pai syndrome: a review. Childs Nerv Syst. 2020 Nov;36(11):2635-2640.
Pashaj S, Merz E. Detection of Fetal Corpus Callosum Abnormalities by Means of 3D Ultrasound. Ultraschall Med. 2016 Apr;37(2):185-94.
Popa RT, Feier D, Fufezan O, Blaga L. Interhemispheric lipoma associated with agenesis of corpus callosum in an infant: case report. Med Ultrason. 2010 Sep;12(3):249-52.
Renkema RW, Caron CJJM, Wolvius EB, Dunaway DJ, Forrest CR, Padwa BL, Koudstaal MJ. Central nervous system anomalies in craniofacial microsomia: a systematic review. Int J Oral Maxillofac Surg. 2018 Jan;47(1):27-34.
s
u
m
m
a
r
y
examples
lipoma of the corpus callosum
The basic anomaly seems to be abnormal differentiation of residual primitive meningeal tissue within the cranium. Extraosseous lipoma or alopecia may alert the clinician. Whereas less than 5 % of all callosal ageneses are associated with lipoma, in reverse 50 % of all fetal brain lipomas are linked with callosal maldevelopment. The lesion is often found in children with spinal dysraphism. One peculiar association is frontonasal dysplasia [hypertelorism, bifid nose, agenesis of corpus callosum and frontal interhemispheric lipoma]. Other associations are between CMV fetopathy and callosal lipoma/agenesis, and between callosal lipoma and Goldenhar syndrome.
Pai syndrome is a rare condition with midline craniofacial abnormalities. It was originally described
as the presence of a median cleft lip, cutaneous polyps of the nasal mucosa and face, and midline lipomas of the central nervous system, mostly at the corpus
callosum (Castori et al. 2007, Olivero et al. 2020).
>
(Boechat et al. 1983, Fisher and Cremin 1988, Melin and Keller 1992)
A lipoma of the corpus callosum is a hyperechoic mass in the middle of the interhemispheric fissure, dorsally between the hemispheres or in choroid plexus of lateral or third ventricle. Curvilinear lipomas replace the caudal corpus callosum and can extend into lateral ventricle choroid plexus. Choroidal extension of a midline lipoma is not seen with presence of the corpus callosum. Tuberonodal lipomas lie adjacent to genu and trunk of the corpus callosum and can extend to the calvarial bone.
With extension into the ventricle cavities the initial suspicion of GMH/IVH in a preterm infant should be corrected by serial scanning (Imaizumi et al. 1988).
The mass corresponds to a sharply delineated hypodensity on CT, often with a shell of calcifications. Fat is hyperintense on both T1 and T2 MRI. Ordinarily the normal corpus callosum has been replaced by this lipoma. On fetal ultrasound, the main feature leading to detection is a short corpus callosum (Attalah et al. 2018). This callosal dysgenesis is associated with a band of hyperechogenicity surrounding tit, mimicking the pericallosal sulcus, increasing in size during the third trimester in some fetuses.
On T2-MRI, this band shows typical hypointensity (darkness); in contrast, on T1-weighted imaging the postnatal expected high signal (brightness) of the lipoma may be absent in utero. Increasing detection rates in utero are expected with advancing 3D ultrasound (Pashaj and Merz 2016). Lipomas do not have high flow vessels (Gradowska et al. 2011)
surprise finding in near term infant
34w GA, trisomy 18
35 w GA, IUGR, preauricular tags
lipoma of the corpus callosum: examples
lipoma of the corpus callosum: summary
Mac OS X 2Û
ATTR
Ü1Ücom.apple.TextEncodingë com.apple.provenanceöcom.apple.quarantineutf-8;134217984Â. Im0ÖWq/0082;6a95926c;Hype4;